Saturday, February 28, 2015

The Epigenetics Revolution


The Epigenetics Revolution: How Modern Biology Is Rewriting Our Understanding of Genetics, Disease, and Inheritance Paperback – October 1, 2013

Author: Visit Amazons Nessa Carey Page | Language: English | ISBN: 0231161174 | Format: PDF, EPUB

  • Description
  • Book Details
  • Table of Contents
  • Reviews
The Epigenetics Revolution: How Modern Biology Is Rewriting Our Understanding of Genetics, Disease, and Inheritance – October 1, 2013
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Review

Anyone seriously interested in who we are and how we function should read this book.

(Peter Forbes The Guardian)

Nessa Carey takes us on a lively and up-to-date tour of whats known about epigenetic mechanisms and their implications for ageing and cancer.

(Laurence Hurst, University of Bath Focus Magazine)

[Nessa Careys] book combines an easy style with a textbooks thoroughness.... A bold attempt to bring epigenetics to a wide audience.

(Jonathan Weitzman Nature)

Careys report on the rapidly developing state of epigenetics research may help nonscientists with public-policy, investment, and health-care decisions.

(Booklist)

An exhilarating exploration of an exciting new field, and a good gift for a bright biologystudent looking for a career choice.

(Kirkus Reviews)

An enlightening introduction to what scientists have learned in the past decade about [epigenetics].

(Carl Zimmer The Wall Street Journal)

This book provides an excellent introduction to a fascinating new field that may revolutionize our understanding of human health and disease. Highly recommended.

(Library Journal)

A must-read for every intelligent person who likes to know what is going on in modern science.

(Graham Storrs New York Journal of Books)

she provides an excellent and largely accurate account of a fascinating and fast-moving area of modern biology.

(Jonathan Hodgkin Times Literary Supplement)

Written in an engaging manner using everyday metaphors to clarify complex concepts and utilizing well--defined diagrams, the author has produced an outstanding book with her wit and expertise.

(Rita Hoots NSTA Recommends (National Science Teachers Association))

About the Author

Nessa Carey is a visiting professor at Imperial College in London and currently works in the biotechnology and pharmaceutical industries, where she has specialized in epigenetics for nearly a decade. She has strong relationships with leading epigenetics researchers, medical labs in Europe, and with some of the most prestigious institutions in the United States, including the Harvard Medical School, the MD Anderson Cancer Center, and the Wistar Institute.


Download latest books on mediafire and other links compilation The Epigenetics Revolution: How Modern Biology Is Rewriting Our Understanding of Genetics, Disease, and Inheritance Paperback – October 1, 2013
  • Paperback: 352 pages
  • Publisher: Columbia University Press; Reprint edition (October 1, 2013)
  • Language: English
  • ISBN-10: 0231161174
  • ISBN-13: 978-0231161176
  • Product Dimensions: 9 x 6.1 x 0.7 inches
  • Shipping Weight: 14.9 ounces (View shipping rates and policies)
  • Amazon Best Sellers Rank: #13,093 in Books (See Top 100 in Books)
    • #3 in Books > Textbooks > Medicine & Health Sciences > Medicine > Basic Sciences > Genetics
    • #6 in Books > Science & Math > Biological Sciences > Biology > Molecular Biology
    • #7 in Books > Medical Books > Basic Sciences > Cell Biology
This is one of those books that introduces an entirely new and fascinating topic. A similar work would be Chaos: Making a New Science which introduced the concepts of chaotic dynamical systems at a time when even many practitioners of the sciences would not have heard of it.

Similarly, this book introduces the discoveries in epigenetics (epi- meaning "on", or a layer on top of classical genetics) and pretty much all of this will be new information unless you have been actively working in the field of cell biology over the past few years.

The book talks about the paradigm shift that is occurring as cell biologists are realizing that this epigenetic information is as complex and important to the correct function of life as the underlying DNA genome, and even allows for Lamarckian inheritance in certain cases where an offsprings own epigenetic information and phenotype can be influenced by that of the parents, meaning that some environmental effects in a parents life can directly influence future generations.

Also much of the non-protein-coding genome that for many years was considered to be unimportant "junk" is now turning out to be very important as it can be transcribed into functional RNA molecules that perform important functions. The book contains a simple graphic showing that the ratio of the non-protein-coding DNA to that of traditional protein coding genes increases in direct proportion with the complexity of the organism. The fundamental genes and proteins between say a chimpanzee and a human are virtually identical and it now begins to look as though its that "junk" DNA that makes all the difference.

The Epigenetics Revolution: How Modern Biology Is Rewriting Our Understanding of Genetics, Disease, and Inheritance – October 1, 2013 Download

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